Manual of Love is a 2005 Italian blockbuster romantic comedy film in four quartets. Each of the four episodes follows a different couple, focusing on a particular stage of a typical love relationship:

• Innamoramento (falling in love): Giulia and Tommaso (Jasmine Trinca and Silvio Muccino) meet and fall in love;
• Crisi (crisis): Barbara and Marco (Margherita Buy and Sergio Rubini) are a couple going through a crisis, close to divorce;
• Tradimento (cheating): A traffic police woman named Ornella (Luciana Littizzetto) is cheated on by her husband and takes revenge;
• Abbandono (break-up): Goffredo (Carlo Verdone) is a rich doctor abandoned by his wife.

The characters in the movie are all related in one way or another, and each transition brings background characters from a previous episode to be the protagonists of the next episode. The film is set in Rome.